Abstract 11.1.3




Prevalence of Metabolic Syndrome in Chronic Kidney Disease


I.S.I. Ogbu1, A.E. Udoh2, C.K. Ijoma3 and H.M. Etukudo2 

1Department of Medical Laboratory Sciences, College of Medicine, University of Nigeria,

Enugu Campus, Nigeria.

2Department of Medical Laboratory Sciences, Chemical Pathology Unit, University of Calabar, Calabar, Nigeria.

3Department of Medicine, College of Medicine, University of Nigeria, Enugu Campus, Nigeria.


Abstract: The prevalence of the metabolic syndrome (MS) among chronic kidney disease patients of Nigerian origin was determined. One hundred and sixty eight, (168), chronic kidney disease outpatients, (86 men and 82 women), aged 35 years and above, recruited from the Nephrology outpatient clinics of the University of Nigeria Teaching Hospital, Enugu southeast Nigeria, participated in the study. The National Cholesterol Education Programme: Adult Treatment Panel 111(ATP 111) criteria were used to diagnose MS. An MS prevalence of 41% was recorded. More male (44.1%) than female (36.6%) patients had the syndrome. Fasting hyperglycaemia, hypertriglyceridaemia, low high density lipoprotein cholesterol (HDLc), excess waist circumference (WC), raised systolic  and diastolic blood pressure, were recorded in 31%, 58.3%, 29.3%, 29.8%, 72.0% and 47.6% respectively of the patients. However, 69.2%, 57.1%, 83.3%, 60%, 47.5% and 42.5% respectively of these abnormal results were associated with the MS. The most common abnormality among the patients was raised systolic blood pressure, (72.6%); followed by elevated serum triglycerides (58.3%).  The prevalence of the metabolic syndrome (41%) among the chronic kidney disease patients was moderately high. Hypertension, hypertriglyceridaemia and hyperglycaemia were the common disorders contributing to the high prevalence.  Strong predictors in male patients were raised WC, low HDLc, and hyperglycaemia.


Key words: metabolic syndrome, chronic kidney disease, lipid profile, ATP 111 criteria.


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