Abstract 6.14



Antimycotic Effects of Jatropha curcas Seed Extracts: Findings from a Preliminary Study


G.T. Jombo, M.N. Enenebeaku, J. Ayeni, O. Fagbemi, E. Mbaawuaga 




The global prevalence of fungal diseases has been on steady increase over the past two decades as a result of acquired immunodeficiency syndrome (AIDS). There is need for continous search for more potent antifungal drugs. Jatropha curcas seeds were extracted using methanol and lyophillization and the extract tested against Candida albicans, Trichosporon biegelii, Tricophyton mentagropytes, Trichophyton verrucosum, and Aspergillus fumigatus using standard laboratory procedures. The minimum inhibitory concentration (MIC) of the extracts was carried out and the results were analysed using simple descriptive methods. C. albicans, T. biegelii, T. mentagrophytes, and T. verrucosum were susceptible to both the methanol and lyophilized seed extracts of J. curcas while A. fumigatus was resistant to both J. curcas seed extracts are potential antifungal drugs; hence effots should be made to identify the actual active ingredients and standardize the dosage for possible human consumption.

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