Abstract 6.  (2)7




Human Immunodeficiency Virus Infection in Patients with Persistent Peripheral Lymphadenopathy in Calabar




A. Etiuma, A. Essiet, I. Ekanem 


Human Immunodeficiency Virus (HIV) infection is associated with persistent generalized lymphadenopathy at some stage of its evolution in many patients. The aim of this prospective study was to assess the prevalence of HIV infection in patients presenting with persistent peripheral lymphadenopathy in Calabar. Lymph node biopsy and HIV serological test using Immuno Comb test were carried out in patients of all ages and sex presenting with persistent lymphadenopathy in Calabar from January 1999 to December 2000. Out of 205 patients studied, 41 (20%) were HIV sero-positive. Patients with histologic diagnosis of reactive lymph node hyperplasia and tuberculosis had higher HIV prevalence of 28.4% and 27.8% respectively. Only 12.3% of those with malignant lymph node diseases were HIV positive in this study. It is concluded that persistent lymphadenopathy is strongly associated with HIV infection in Calabar. All patients with persistent lymphadenopathy should be screenedroutinely for HIV infection.


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