Abstract 6.  (1)1
 

 

 

Assessment of Some Haematological Parameters in HIV Infected Patients on Anti-Retroviral Herbal Preparation (“Winnie Cure”) in Nigeria

 

N. E. Udonwa1, O. F. Emelilke2, E. K. Uko2, E. J. Peters3, N. Jean4 and J. Abdulahi

 

1 Department of Family Medicine, University of Calabar Teaching Hospital, Calabar, Nigeria

2 Department of Haematology and Blood Transfusion, University of Calabar, Calabar Nigeria

3 Departments of Medicine, University of Calabar, Calabar, Nigeria

4 Winners Medical Diagnostic and Research Institute, Abuja, Nigeria

 

Abstract: The study was to assess the haematological parameters [Haemoglobin (Hb), packed cell volume (PCV), total white blood cells (TWBC), differential White Blood Cells (WBC), platelet count and erythrocyte sedimentation rate (ESR)] of confirmed thirty-one (31) HIV patients before and after being treated with a herbal preparation called Winnie Cure(R), a supposed anti-retroviral agent. The preparation was prescribed at a dose of 5ml (one tea spoonful) containing 250mg Winnie Cure(R) extract, taken three times daily for five days and then two times daily for the period of this study (nine weeks). Samples were collected from the 31 confirmed HIV infected patients on their visit (before they started the treatment) and at three weeks interval from the time they started treatment till the 9th week (second, third and fourth visit). Blood collected was by standard veno-puncture method while ESR was estimated by Westergrene method. Other haematological parameters were evaluated using Coulter ACT diff Analyzer. At the first, second third and forth visits the ESR (mm/h) values obtained were decreasing thus indicating a positive patient response to the drug. It was observed that all the parameters showed significant variation at the 3rd visit, with platelets and PCV values being significantly raised at the 3rd visit (six weeks of treatment). We observed that this herbal preparation (Winnie Cure ®) seems to attain peak activity at 3rd and 4th visits (that is the sixth and ninth weeks of treatment), as indicated by appreciative changes of some haematological parameters. Clinical and pharmaceutical evaluation of this preparation for possible use in the treatment of HIV patients is suggested.

Key words: Anti-Retroviral, Herbal Preparation, Haematological Parameters, Nigeria.

 

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