article 10. 14
 

 

 

Human Papillomavirus  Infection In cervical Tissue of Patients Visiting University of Calabar Teaching Hospital, Calabar, Nigeria.

 

A.  W.   Essien

Department of Pathology,

University of Calabar Teaching Hospital,

P. M. B. 1278, Calabar, Nigeria.       

 

A.  R.   Udoh 

Department of Pathology,

University of Calabar Teaching Hospital,

P. M. B. 1278, Calabar, Nigeria.  

 

P.  C.   Inyang-Etoh

Department of Medical Laboratory Science,

Faculty of Allied Medical Sciences,              

College of Medical Sciences,

University of Calabar, Calabar, Nigeria.

 

 V.  I.   Umanah

Department of Medical Laboratory Science,

Faculty of Allied Medical Sciences,              

College of Medical Sciences,

University of Calabar, Calabar, Nigeria.

 

 

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Abstract

Abstract: Studies on tissues of cervical tumours from 42 women aged 20 to 75years who visited UCTH, Calabar between 2006 and 2009 were carried out to assess the presence of Human Papilloma Virus (HPV) particles using two histological staining techniques; Haematoxylin/Eosin and Phloxine-tartrazine respectively. Of the 42 tumours, 30(71.4%) were malignant and 12(28.6%) were benign. In both the Haematoxylin and Eosin (H/E) and Phloxine-tartrazine staining techniques, 30(71.4%) of the 42 tumours were positive for Human Papilloma Virus. The mean ages of women having HPV infection and cervical tumours were 45 19 years. There was no statistically significant difference between the distribution of the cervical tumours and HPV by age (P>0.05). There was a strong positive correlation between the presence of HPV and cervical tumours (r = 8.1).  This work has shown HPV to be associated with cervical cancer. We therefore advocate the need of cytologic screening of women within this age group of 25 75 years to facilitate the early identification of women at risk. Early detection and treatment of precancerous lesions can prevent progression to cervical cancer.  Early detection of high-risk HPV types may improve trial, treatment, and follow-up in infected patients.

 

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